Nickel-catalysed aromatic Finkelstein reaction of aryl and heteroaryl bromides.
نویسندگان
چکیده
A fast and efficient nickel-catalysed iodination reaction of aryl and heteroaryl bromides has been developed. The transformation was found to be general for a wide range of substrates and was used for the synthesis of iodo-PK11195, an imaging agent of Alzheimer's disease and iniparib, a compound used in the treatment of breast cancer.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 33 شماره
صفحات -
تاریخ انتشار 2012